P-Bodies React to Stress and Nonsense
نویسندگان
چکیده
P-bodies are specialized cytoplasmic compartments where translational repression and mRNA turnover may occur. Findings in this issue of Cell provide evidence that P-bodies are sites of "mRNA purgatory." Bhattacharyya et al. (2006) reveal that normal mRNA can be released from P-bodies and translated into protein in response to stress. Meanwhile, Sheth and Parker (2006) report that aberrant mRNAs are targeted to P-bodies to undergo rapid decay.
منابع مشابه
UPF1 P-body localization.
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ورودعنوان ژورنال:
- Cell
دوره 125 شماره
صفحات -
تاریخ انتشار 2006